Pseudomonas aeruginosa Cif defines a distinct class of α/β epoxide hydrolases utilizing a His/Tyr ring-opening pair

מאת Bahl, Christopher D., Madden, Dean R.
יצא לאור 2012

Integration of the Rosetta suite with the python software stack via reproducible packaging and core programming interfaces for distributed simulation

מאת Ford, Alexander S., Weitzner, Brian D., Bahl, Christopher D.
הוצא לאור ב Protein Sci (2019)

Toward complete rational control over protein structure and function through computational design

מאת Adolf-Bryfogle, Jared, Teets, Frank D., Bahl, Christopher D.
הוצא לאור ב Curr Opin Struct Biol (2020)

Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted by Pseudomonas aeruginosa

מאת Bahl, Christopher D., MacEachran, Daniel P., O’Toole, George A., Madden, Dean R.
יצא לאור 2009

Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP

מאת Amacher, Jeanine F., Cushing, Patrick R., Bahl, Christopher D., Beck, Tobias, Madden, Dean R.
יצא לאור 2013

Visualizing the mechanism of epoxide hydrolysis by the bacterial virulence enzyme Cif

מאת Bahl, Christopher D., Hvorecny, Kelli L., Morisseau, Christophe, Gerber, Scott A., Madden, Dean R.
הוצא לאור ב Biochemistry (2016)

Inhibiting an epoxide hydrolase virulence strategy protects CFTR

מאת Bahl, Christopher D., Hvorecny, Kelli L., Bomberger, Jennifer M., Stanton, Bruce A., Hammock, Bruce D., Morisseau, Christophe, Madden, Dean R.
הוצא לאור ב Angew Chem Int Ed Engl (2015)

Active-site flexibility and substrate specificity in a bacterial virulence factor: crystallographic snapshots of an epoxide hydrolase

מאת Hvorecny, Kelli L., Bahl, Christopher D., Kitamura, Seiya, Lee, Kin Sing Stephen, Hammock, Bruce D., Morisseau, Christophe, Madden, Dean R.
הוצא לאור ב Structure (2017)

Crystal Structure of the Cystic Fibrosis Transmembrane Conductance Regulator Inhibitory Factor Cif Reveals Novel Active-Site Features of an Epoxide Hydrolase Virulence Factor

מאת Bahl, Christopher D., Morisseau, Christophe, Bomberger, Jennifer M., Stanton, Bruce A., Hammock, Bruce D., O'Toole, George A., Madden, Dean R.
יצא לאור 2010

The cif Virulence Factor is Present in Keratitis Patient Isolates of Pseudomonas aeruginosa

מאת Bahl, Christopher D., St. Laurent, Jessica D., Karthikeyan, R. Siva Ganesa, Priya, J. Lakshmi, Prajna, Lalitha, Zegans, Michael E., Madden, Dean R.
הוצא לאור ב Cornea (2017)

Signature Motifs Identify an Acinetobacter Cif Virulence Factor with Epoxide Hydrolase Activity

מאת Bahl, Christopher D., Hvorecny, Kelli L., Bridges, Andrew A., Ballok, Alicia E., Bomberger, Jennifer M., Cady, Kyle C., O'Toole, George A., Madden, Dean R.
יצא לאור 2014

Epoxide-Mediated CifR Repression of cif Gene Expression Utilizes Two Binding Sites in Pseudomonas aeruginosa

מאת Ballok, Alicia E., Bahl, Christopher D., Dolben, Emily L., Lindsay, Allia K., St. Laurent, Jessica D., Hogan, Deborah A., Madden, Dean R., O'Toole, George A.
יצא לאור 2012

Discovery and engineering of enhanced SUMO protease enzymes

מאת Lau, Yue-Ting K., Baytshtok, Vladimir, Howard, Tessa A., Fiala, Brooke M., Johnson, JayLee M., Carter, Lauren P., Baker, David, Lima, Christopher D., Bahl, Christopher D.
הוצא לאור ב J Biol Chem (2018)

Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide‐rich de novo designed peptides

מאת Buchko, Garry W., Pulavarti, Surya V.S.R.K., Ovchinnikov, Victor, Shaw, Elizabeth A., Rettie, Stephen A., Myler, Peter J., Karplus, Martin, Szyperski, Thomas, Baker, David, Bahl, Christopher D.
הוצא לאור ב Protein Sci (2018)

Biochemical and structural characterization of two cif-like epoxide hydrolases from Burkholderia cenocepacia

מאת Taher, Noor M., Hvorecny, Kelli L., Burke, Cassandra M., Gilman, Morgan S.A., Heussler, Gary E., Adolf-Bryfogle, Jared, Bahl, Christopher D., O'Toole, George A., Madden, Dean R.
הוצא לאור ב Curr Res Struct Biol (2021)

Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis

מאת Gao, Melody, Mackley, Iain G. P., Mesbahi‐Vasey, Samaneh, Bamonte, Haley A., Struyvenberg, Sarah A., Landolt, Louisa, Pederson, Nick J., Williams, Lucy I., Bahl, Christopher D., Brooks, Lionel, Amacher, Jeanine F.
הוצא לאור ב Protein Sci (2020)

An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung

מאת Hvorecny, Kelli L., Dolben, Emily, Moreau-Marquis, Sophie, Hampton, Thomas H., Shabaneh, Tamer B., Flitter, Becca A., Bahl, Christopher D., Bomberger, Jennifer M., Levy, Bruce D., Stanton, Bruce A., Hogan, Deborah A., Madden, Dean R.
הוצא לאור ב Am J Physiol Lung Cell Mol Physiol (2018)

Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators

מאת Flitter, Becca A., Hvorecny, Kelli L., Ono, Emiko, Eddens, Taylor, Yang, Jun, Kwak, Daniel H., Bahl, Christopher D., Hampton, Thomas H., Morisseau, Christophe, Hammock, Bruce D., Liu, Xinyu, Lee, Janet S., Kolls, Jay K., Levy, Bruce D., Madden, Dean R., Bomberger, Jennifer M.
הוצא לאור ב Proc Natl Acad Sci U S A (2017)

Screening, large-scale production, and structure-based classification for cystine-dense peptides

מאת Correnti, Colin E., Gewe, Mesfin M., Mehlin, Christopher, Bandaranayake, Ashok D., Johnsen, William A., Rupert, Peter B., Brusniak, Mi-Youn, Clarke, Midori, Burke, Skyler E., de van der Schueren, Willem, Pilat, Kristina, Turnbaugh, Shanon M., May, Damon, Watson, Alex, Chan, Man Kid, Bahl, Christopher D., Olson, James M., Strong, Roland K.
הוצא לאור ב Nat Struct Mol Biol (2018)

Accurate de novo design of hyperstable constrained peptides

מאת Bhardwaj, Gaurav, Mulligan, Vikram Khipple, Bahl, Christopher D., Gilmore, Jason M., Harvey, Peta J., Cheneval, Olivier, Buchko, Garry W., Pulavarti, Surya V.S.R.K., Kaas, Quentin, Eletsky, Alexander, Huang, Po-Ssu, Johnsen, William A., Greisen, Per, Rocklin, Gabriel J., Song, Yifan, Linsky, Thomas W., Watkins, Andrew, Rettie, Stephen A., Xu, Xianzhong, Carter, Lauren P., Bonneau, Richard, Olson, James M., Coutsias, Evangelos, Correnti, Colin E., Szyperski, Thomas, Craik, David J., Baker, David
הוצא לאור ב Nature (2016)