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Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP

PDZ (PSD-95/Dlg/ZO-1) binding domains often serve as cellular traffic engineers, controlling the localization and activity of a wide variety of binding partners. As a result, they play important roles in both physiological and pathological processes. However, PDZ binding specificities overlap, allow...

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Bibliographische Detailangaben
Hauptverfasser: Amacher, Jeanine F., Cushing, Patrick R., Bahl, Christopher D., Beck, Tobias, Madden, Dean R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576116/
https://ncbi.nlm.nih.gov/pubmed/23243314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.401588
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