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Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor
Cystic fibrosis (CF) is associated with loss-of-function mutations in the CF transmembrane conductance regulator (CFTR), which regulates epithelial fluid and ion homeostasis. The CFTR cytoplasmic C-terminus interacts with a number of PDZ (PSD-95/Dlg/ZO-1) proteins that modulate its intracellular tra...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
International Union of Crystallography
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087650/ https://ncbi.nlm.nih.gov/pubmed/21543871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111009985 |
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