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Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain
PDZ domains are protein-protein interaction modules that coordinate multiple signaling and trafficking pathways in the cell and that include active therapeutic targets for diseases such as cancer, cystic fibrosis, and addiction. Our previous work characterized a PDZ interaction that restricts the ap...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138078/ https://ncbi.nlm.nih.gov/pubmed/25136860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103650 |
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