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Bivalent Peptides as PDZ Domain Ligands

A series of multivalent peptides with the ability to simultaneously bind two separate PDZ domain proteins has been designed, synthesized and tested by isothermal titration calorimetry (ITC). The monomer sequences, linked with succinate, varied in length from five to nine residues. The thermodynamic...

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Bibliografske podrobnosti
Main Authors: Klosi, Edvin, Saro, Dorina, Spaller, Mark R.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169291/
https://ncbi.nlm.nih.gov/pubmed/17890086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.09.035
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