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A Thermodynamic Ligand Binding Study of the Third PDZ Domain (PDZ3) from the Mammalian Neuronal Protein PSD-95

The thermodynamic parameters associated with the binding of several series of linear peptides to the third PDZ domain (PDZ3) of the postsynaptic density 95 protein (PSD-95) have been measured using isothermal titration calorimetry (ITC). Two strategies were pursued in developing these binding ligand...

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Detalhes bibliográficos
Main Authors: Saro, Dorina, Li, Tao, Rupasinghe, Chamila, Paredes, Azrael, Caspers, Nicole, Spaller, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527733/
https://ncbi.nlm.nih.gov/pubmed/17474715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062088k
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