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Addressing the role of the α-helical extension in the folding of the third PDZ domain from PSD-95

PDZ domains are one of the most important protein-protein interaction domains in human. While presenting a conserved three dimensional structure, a substantial number of PDZ domains display structural extensions suggested to be involved in their folding and binding mechanisms. The C-terminal α-helix...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Gautier, Candice, Visconti, Lorenzo, Jemth, Per, Gianni, Stefano
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626748/
https://ncbi.nlm.nih.gov/pubmed/28974728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12827-0
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