Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer

GIPC (GAIP-interacting protein, C terminus) represents a new target class for the discovery of chemotherapeutics. While many of the current generation of anticancer agents function by directly binding to intracellular kinases or cell surface receptors, the disruption of cytosolic protein-protein int...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Patra, Chitta Ranjan, Rupasinghe, Chamila N., Dutta, Shamit K, Bhattacharya, Santanu, Wang, Enfeng, Spaller, Mark R., Mukhopadhyay, Debabrata
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331932/
https://ncbi.nlm.nih.gov/pubmed/22292614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200536r
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