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Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain
PDZ domains are protein-protein interaction modules that coordinate multiple signaling and trafficking pathways in the cell and that include active therapeutic targets for diseases such as cancer, cystic fibrosis, and addiction. Our previous work characterized a PDZ interaction that restricts the ap...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138078/ https://ncbi.nlm.nih.gov/pubmed/25136860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103650 |
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