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Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain

PDZ domains are protein-protein interaction modules that coordinate multiple signaling and trafficking pathways in the cell and that include active therapeutic targets for diseases such as cancer, cystic fibrosis, and addiction. Our previous work characterized a PDZ interaction that restricts the ap...

詳細記述

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書誌詳細
主要な著者: Amacher, Jeanine F., Zhao, Ruizhi, Spaller, Mark R., Madden, Dean R.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138078/
https://ncbi.nlm.nih.gov/pubmed/25136860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103650
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