Epoxide-Mediated CifR Repression of cif Gene Expression Utilizes Two Binding Sites in Pseudomonas aeruginosa

Pseudomonas aeruginosa secretes an epoxide hydrolase virulence factor that reduces the apical membrane expression of ABC transporters such as the cystic fibrosis transmembrane conductance regulator (CFTR). This virulence factor, named CFTR inhibitory factor (Cif), is regulated by a TetR-family, epox...

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Главные авторы: Ballok, Alicia E., Bahl, Christopher D., Dolben, Emily L., Lindsay, Allia K., St. Laurent, Jessica D., Hogan, Deborah A., Madden, Dean R., O'Toole, George A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457200/
https://ncbi.nlm.nih.gov/pubmed/22843844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00984-12
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