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Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted by Pseudomonas aeruginosa

The opportunistic pathogen Pseudomonas aeruginosa secretes a protein that triggers the accelerated degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells. This protein, which is known as the CFTR inhibitory factor (Cif), acts as a virulence factor an...

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Detalhes bibliográficos
Main Authors: Bahl, Christopher D., MacEachran, Daniel P., O’Toole, George A., Madden, Dean R.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805529/
https://ncbi.nlm.nih.gov/pubmed/20057063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109047599
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