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Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted by Pseudomonas aeruginosa

The opportunistic pathogen Pseudomonas aeruginosa secretes a protein that triggers the accelerated degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells. This protein, which is known as the CFTR inhibitory factor (Cif), acts as a virulence factor an...

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Main Authors: Bahl, Christopher D., MacEachran, Daniel P., O’Toole, George A., Madden, Dean R.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805529/
https://ncbi.nlm.nih.gov/pubmed/20057063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109047599
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