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Inhibiting an epoxide hydrolase virulence strategy protects CFTR
Opportunistic pathogens exploit diverse strategies to sabotage host defenses. Pseudomonas aeruginosa secretes the CFTR inhibitory factor Cif and thus triggers loss of CFTR, an ion channel required for airway mucociliary defense. However, Cif's mechanism of action has remained unclear. It cataly...
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| 出版年: | Angew Chem Int Ed Engl |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556431/ https://ncbi.nlm.nih.gov/pubmed/26136396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201503983 |
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