Inhibiting an epoxide hydrolase virulence strategy protects CFTR

Opportunistic pathogens exploit diverse strategies to sabotage host defenses. Pseudomonas aeruginosa secretes the CFTR inhibitory factor Cif and thus triggers loss of CFTR, an ion channel required for airway mucociliary defense. However, Cif's mechanism of action has remained unclear. It cataly...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Bahl, Christopher D., Hvorecny, Kelli L., Bomberger, Jennifer M., Stanton, Bruce A., Hammock, Bruce D., Morisseau, Christophe, Madden, Dean R.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556431/
https://ncbi.nlm.nih.gov/pubmed/26136396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201503983
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars