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Inhibiting an epoxide hydrolase virulence strategy protects CFTR
Opportunistic pathogens exploit diverse strategies to sabotage host defenses. Pseudomonas aeruginosa secretes the CFTR inhibitory factor Cif and thus triggers loss of CFTR, an ion channel required for airway mucociliary defense. However, Cif's mechanism of action has remained unclear. It cataly...
Tallennettuna:
| Julkaisussa: | Angew Chem Int Ed Engl |
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| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556431/ https://ncbi.nlm.nih.gov/pubmed/26136396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201503983 |
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