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Visualizing the mechanism of epoxide hydrolysis by the bacterial virulence enzyme Cif
The CFTR inhibitory factor (Cif) is an epoxide hydrolase (EH) virulence factor secreted by the bacterium Pseudomonas aeruginosa. Sequence alignments reveal a pattern of Cif-like substitutions that proved to be characteristic of a new subfamily of bacterial EHs. At the same time, crystallographic and...
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| Udgivet i: | Biochemistry |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4765904/ https://ncbi.nlm.nih.gov/pubmed/26752215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01229 |
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