Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide‐rich de novo designed peptides

Disulfide‐rich peptides represent an important protein family with broad pharmacological potential. Recent advances in computational methods have made it possible to design new peptides which adopt a stable conformation de novo. Here, we describe a system to produce disulfide‐rich de novo peptides u...

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Detaylı Bibliyografya
Yayımlandı:Protein Sci
Asıl Yazarlar: Buchko, Garry W., Pulavarti, Surya V.S.R.K., Ovchinnikov, Victor, Shaw, Elizabeth A., Rettie, Stephen A., Myler, Peter J., Karplus, Martin, Szyperski, Thomas, Baker, David, Bahl, Christopher D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Inc. 2018
Konular:
Full‐Length Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194292/
https://ncbi.nlm.nih.gov/pubmed/30152054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3453
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