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Computational de novo design of a four-helix bundle protein—DND_4HB

The de novo design of proteins is a rigorous test of our understanding of the key determinants of protein structure. The helix bundle is an interesting de novo design model system due to the diverse topologies that can be generated from a few simple α-helices. Previously, noncomputational studies de...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Murphy, Grant S, Sathyamoorthy, Bharatwaj, Der, Bryan S, Machius, Mischa C, Pulavarti, Surya V, Szyperski, Thomas, Kuhlman, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380976/
https://ncbi.nlm.nih.gov/pubmed/25287625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2577
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