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Rational thermostabilisation of four-helix bundle dimeric de novo proteins
The stability of proteins is an important factor for industrial and medical applications. Improving protein stability is one of the main subjects in protein engineering. In a previous study, we improved the stability of a four-helix bundle dimeric de novo protein (WA20) by five mutations. The stabil...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8024369/ https://ncbi.nlm.nih.gov/pubmed/33824364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86952-2 |
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