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De Novo Design of Metalloproteins and Metalloenzymes in a Three-Helix Bundle

For more than two decades, de novo protein design has proven to be an effective methodology for modeling native proteins. De novo design involves the construction of metal-binding sites within simple and/or unrelated α-helical peptide structures. The preparation of α(3)D, a single polypeptide that f...

詳細記述

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書誌詳細
出版年:Methods Mol Biol
主要な著者: Plegaria, Jefferson S., Pecoraro, Vincent L.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708869/
https://ncbi.nlm.nih.gov/pubmed/27094292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3569-7_11
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