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De Novo Design of Metalloproteins and Metalloenzymes in a Three-Helix Bundle

For more than two decades, de novo protein design has proven to be an effective methodology for modeling native proteins. De novo design involves the construction of metal-binding sites within simple and/or unrelated α-helical peptide structures. The preparation of α(3)D, a single polypeptide that f...

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Bibliografiska uppgifter
I publikationen:Methods Mol Biol
Huvudupphovsmän: Plegaria, Jefferson S., Pecoraro, Vincent L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708869/
https://ncbi.nlm.nih.gov/pubmed/27094292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3569-7_11
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