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Artificial metalloenzymes derived from three-helix bundles

Three-helix bundles and coiled-coil motifs are well-established de novo designed scaffolds that have been investigated for their metal-binding and catalytic properties. Satisfaction of the primary coordination sphere for a given metal is sufficient to introduce catalytic activity and a given structu...

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Pubblicato in:Curr Opin Chem Biol
Autori principali: Tebo, Alison G., Pecoraro, Vincent L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380837/
https://ncbi.nlm.nih.gov/pubmed/25579452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.12.034
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