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Sculpting Metal-binding Environments in De Novo Designed Three-helix Bundles

De novo protein design is a biologically relevant approach used to study the active centers of native metalloproteins. In this review, we will first discuss the design process in achieving α(3)D, a de novo designed three-helix bundle peptide with a well-defined fold. We will then cover our recent wo...

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Foilsithe in:Isr J Chem
Main Authors: Plegaria, Jefferson S., Pecoraro, Vincent L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771423/
https://ncbi.nlm.nih.gov/pubmed/29353917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201400146
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