Loading...

Sculpting Metal-binding Environments in De Novo Designed Three-helix Bundles

De novo protein design is a biologically relevant approach used to study the active centers of native metalloproteins. In this review, we will first discuss the design process in achieving α(3)D, a de novo designed three-helix bundle peptide with a well-defined fold. We will then cover our recent wo...

Full description

Saved in:
Bibliographic Details
Published in:Isr J Chem
Main Authors: Plegaria, Jefferson S., Pecoraro, Vincent L.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771423/
https://ncbi.nlm.nih.gov/pubmed/29353917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201400146
Tags: Add Tag
No Tags, Be the first to tag this record!