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Sculpting Metal-binding Environments in De Novo Designed Three-helix Bundles

De novo protein design is a biologically relevant approach used to study the active centers of native metalloproteins. In this review, we will first discuss the design process in achieving α(3)D, a de novo designed three-helix bundle peptide with a well-defined fold. We will then cover our recent wo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Isr J Chem
Prif Awduron: Plegaria, Jefferson S., Pecoraro, Vincent L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771423/
https://ncbi.nlm.nih.gov/pubmed/29353917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201400146
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