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Apoprotein Structure and Metal Binding Characterization of a de Novo Designed Peptide, α(3)DIV, that Sequesters Toxic Heavy Metals

De novo protein design is a biologically relevant approach that provides a novel process in elucidating protein folding and modeling the metal centers of metalloproteins in a completely unrelated or simplified fold. An integral step in de novo protein design is the establishment of a well-folded sca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: Plegaria, Jefferson S., Dzul, Stephen P., Zuiderweg, Erik R. P., Stemmler, Timothy L., Pecoraro, Vincent L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492461/
https://ncbi.nlm.nih.gov/pubmed/25790102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00064
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