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A Crystallographic Examination of Predisposition versus Preorganization in de Novo Designed Metalloproteins
Preorganization and predisposition are important molecular recognition concepts exploited by nature to obtain site-specific and selective metal binding to proteins. While native structures containing an MS(3) core are often unavailable in both apo- and holo-forms, one can use designed three-stranded...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5242185/ https://ncbi.nlm.nih.gov/pubmed/27532255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b07165 |
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