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Hydrolytic catalysis and structural stabilization in a designed metalloprotein

Metal ions are an important part of many natural proteins, providing structural, catalytic and electron transfer functions. Reproducing these functions in a designed protein is the ultimate challenge to our understanding of them. Here, we present an artificial metallohydrolase, which has been shown...

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Autori principali: Zastrow, Melissa L., Peacock, Anna F. A., Stuckey, Jeanne A., Pecoraro, Vincent L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270697/
https://ncbi.nlm.nih.gov/pubmed/22270627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1201
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