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Hydrolytic catalysis and structural stabilization in a designed metalloprotein
Metal ions are an important part of many natural proteins, providing structural, catalytic and electron transfer functions. Reproducing these functions in a designed protein is the ultimate challenge to our understanding of them. Here, we present an artificial metallohydrolase, which has been shown...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270697/ https://ncbi.nlm.nih.gov/pubmed/22270627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1201 |
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