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How Outer Coordination Sphere Modifications Can Impact Metal Structures in Proteins: A Crystallographic Evaluation
A challenging objective of de Novo metalloprotein design is to control of the outer coordination spheres of an active site to fine tune metal properties. The well-defined three stranded coiled coils, TRI and CoilSer peptides, are used to address this question. Substitution of Cys for Leu yields a th...
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| Publicat a: | Chemistry |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6510599/ https://ncbi.nlm.nih.gov/pubmed/30861211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201806040 |
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