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Rational thermostabilisation of four-helix bundle dimeric de novo proteins
The stability of proteins is an important factor for industrial and medical applications. Improving protein stability is one of the main subjects in protein engineering. In a previous study, we improved the stability of a four-helix bundle dimeric de novo protein (WA20) by five mutations. The stabil...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8024369/ https://ncbi.nlm.nih.gov/pubmed/33824364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86952-2 |
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