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Artificial Diiron Enzymes with a De Novo Designed Four-Helix Bundle Structure

A single polypeptide chain may provide an astronomical number of conformers. Nature selected only a trivial number of them through evolution, composing an alphabet of scaffolds, that can afford the complete set of chemical reactions needed to support life. These structural templates are so stable th...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Inorg Chem
Hauptverfasser: Chino, Marco, Maglio, Ornella, Nastri, Flavia, Pavone, Vincenzo, DeGrado, William F., Lombardi, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019575/
https://ncbi.nlm.nih.gov/pubmed/27630532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejic.201500470
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