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Preorganization of molecular binding sites in designed diiron proteins

De novo protein design provides an attractive approach to critically test the features that are required for metalloprotein structure and function. Previously we designed and crystallographically characterized an idealized dimeric model for the four-helix bundle class of diiron and dimanganese prote...

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Détails bibliographiques
Auteurs principaux: Maglio, Ornella, Nastri, Flavia, Pavone, Vincenzo, Lombardi, Angela, DeGrado, William F.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC152997/
https://ncbi.nlm.nih.gov/pubmed/12655072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730771100
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