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Computational de novo design of a four-helix bundle protein—DND_4HB

The de novo design of proteins is a rigorous test of our understanding of the key determinants of protein structure. The helix bundle is an interesting de novo design model system due to the diverse topologies that can be generated from a few simple α-helices. Previously, noncomputational studies de...

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Dades bibliogràfiques
Publicat a:Protein Sci
Autors principals: Murphy, Grant S, Sathyamoorthy, Bharatwaj, Der, Bryan S, Machius, Mischa C, Pulavarti, Surya V, Szyperski, Thomas, Kuhlman, Brian
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380976/
https://ncbi.nlm.nih.gov/pubmed/25287625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2577
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