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Computational de novo design of a four-helix bundle protein—DND_4HB

The de novo design of proteins is a rigorous test of our understanding of the key determinants of protein structure. The helix bundle is an interesting de novo design model system due to the diverse topologies that can be generated from a few simple α-helices. Previously, noncomputational studies de...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Protein Sci
Main Authors: Murphy, Grant S, Sathyamoorthy, Bharatwaj, Der, Bryan S, Machius, Mischa C, Pulavarti, Surya V, Szyperski, Thomas, Kuhlman, Brian
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380976/
https://ncbi.nlm.nih.gov/pubmed/25287625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2577
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