Mutations in LRRK2 potentiate age-related impairment of autophagic flux

по Saha, Shamol, Ash, Peter E. A., Gowda, Vivek, Liu, Liqun, Shirihai, Orian, Wolozin, Benjamin
Опубликовано в: Mol Neurodegener (2015)

TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans

по Vaccaro, Alexandra, Tauffenberger, Arnaud, Ash, Peter E. A., Carlomagno, Yari, Petrucelli, Leonard, Parker, J. Alex
Опубликовано 2012

Pathological Stress Granules in Alzheimer’s Disease

по Ash, Peter E.A., Vanderweyde, Tara E., Youmans, Katherine L., Apicco, Daniel J., Wolozin, Benjamin
Опубликовано в: Brain Res (2014)

Neurotoxic effects of TDP-43 overexpression in C. elegans

по Ash, Peter E.A., Zhang, Yong-Jie, Roberts, Christine M., Saldi, Tassa, Hutter, Harald, Buratti, Emanuele, Petrucelli, Leonard, Link, Christopher D.
Опубликовано 2010

TIA1 regulates the generation and response to toxic tau oligomers

по Jiang, Lulu, Ash, Peter E. A., Maziuk, Brandon F., Ballance, Heather I., Boudeau, Samantha, Abdullatif, Ali Al, Orlando, Marcello, Petrucelli, Leonard, Ikezu, Tsuneya, Wolozin, Benjamin
Опубликовано в: Acta Neuropathol (2018)

Heavy Metal Neurotoxicants Induce ALS-Linked TDP-43 Pathology

по Ash, Peter E A, Dhawan, Uma, Boudeau, Samantha, Lei, Shuwen, Carlomagno, Yari, Knobel, Mark, Al Mohanna, Louloua F A, Boomhower, Steven R, Newland, M Christopher, Sherr, David H, Wolozin, Benjamin
Опубликовано в: Toxicol Sci (2019)

5’ UTR variants in the quantitative trait gene Hnrnph1 support reduced 5’ UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity

по Ruan, Qiu T., Yazdani, Neema, Reed, Eric R., Beierle, Jacob A., Peterson, Lucy P., Luttik, Kimberly P., Szumlinski, Karen K., Johnson, William E., Ash, Peter E. A., Wolozin, Benjamin, Bryant, Camron D.
Опубликовано в: FASEB J (2020)

Dioxins and related environmental contaminants increase TDP-43 levels

по Ash, Peter E. A., Stanford, Elizabeth A., Al Abdulatif, Ali, Ramirez-Cardenas, Alejandra, Ballance, Heather I., Boudeau, Samantha, Jeh, Amanda, Murithi, James M., Tripodis, Yorghos, Murphy, George J., Sherr, David H., Wolozin, Benjamin
Опубликовано в: Mol Neurodegener (2017)

RNA binding proteins co-localize with small tau inclusions in tauopathy

по Maziuk, Brandon F., Apicco, Daniel J., Cruz, Anna Lourdes, Jiang, Lulu, Ash, Peter E. A., da Rocha, Edroaldo Lummertz, Zhang, Cheng, Yu, Wai Haung, Leszyk, John, Abisambra, Jose F., Li, Hu, Wolozin, Benjamin
Опубликовано в: Acta Neuropathol Commun (2018)

Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS

по Ash, Peter E.A., Bieniek, Kevin F., Gendron, Tania F., Caulfield, Thomas, Lin, Wen-Lang, DeJesus-Hernandez, Mariely, van Blitterswijk, Marka M., Jansen-West, Karen, Paul, Joseph W., Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard
Опубликовано 2013

Changes in neuronal immunofluorescence in the C- versus N-terminal domains of hnRNP H following D1 dopamine receptor activation

по Ruan, Qiu T., Yazdani, Neema, Beierle, Jacob A., Hixson, Kathryn M., Hokenson, Kristen E., Apicco, Daniel J., Luttik, Kimberly P., Zheng, Karen, Maziuk, Brandon F., Ash, Peter E. A., Szumlinski, Karen K., Russek, Shelley J., Wolozin, Benjamin, Bryant, Camron D.
Опубликовано в: Neurosci Lett (2018)

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity

по Vanderweyde, Tara, Apicco, Daniel J., Youmans-Kidder, Katherine, Ash, Peter E.A., Cook, Casey, da Rocha, Edroaldo Lummertz, Jansen-West, Karen, Frame, Alissa A., Citro, Allison, Leszyk, John D., Ivanov, Pavel, Abisambra, Jose F., Steffen, Martin, Li, Hu, Petrucelli, Leonard, Wolozin, Benjamin
Опубликовано в: Cell Rep (2016)

TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau

по Ash, Peter E. A., Lei, Shuwen, Shattuck, Jenifer, Boudeau, Samantha, Carlomagno, Yari, Medalla, Maria, Mashimo, Bryce L., Socorro, Guillermo, Al-Mohanna, Louloua F. A., Jiang, Lulu, Öztürk, Muhammet M., Knobel, Mark, Ivanov, Pavel, Petrucelli, Leonard, Wegmann, Susanne, Kanaan, Nicholas M., Wolozin, Benjamin
Опубликовано в: Proc Natl Acad Sci U S A (2021)

Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS

по Gendron, Tania F., Bieniek, Kevin F., Zhang, Yong-Jie, Jansen-West, Karen, Ash, Peter E. A., Caulfield, Thomas, Daughrity, Lillian, Dunmore, Judith H., Castanedes-Casey, Monica, Chew, Jeannie, Cosio, Danielle M., van Blitterswijk, Marka, Lee, Wing C., Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard
Опубликовано 2013

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

по Zhang, Yong-Jie, Jansen-West, Karen, Xu, Ya-Fei, Gendron, Tania F., Bieniek, Kevin F., Lin, Wen-Lang, Sasaguri, Hiroki, Caulfield, Thomas, Hubbard, Jaime, Daughrity, Lillian, Chew, Jeannie, Belzil, Veronique V., Prudencio, Mercedes, Stankowski, Jeannette N., Castanedes-Casey, Monica, Whitelaw, Ena, Ash, Peter E. A., DeTure, Michael, Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard
Опубликовано 2014

Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo

по Apicco, Daniel J., Ash, Peter E. A., Maziuk, Brandon, LeBlang, Chelsey, Medalla, Maria, Abdullatif, Ali Al, Ferragud, Antonio, Botelho, Emily, Ballance, Heather I., Dhawan, Uma, Boudeau, Samantha, Cruz, Anna Lourdes, Kashy, Daniel, Wong, Aria, Goldberg, Lisa R., Yazdani, Neema, Zhang, Cheng, Ung, Choong Y, Tripodis, Yorghos, Kanaan, Nicholas M., Ikezu, Tsuneya, Cottone, Pietro, Leszyk, John, Li, Hu, Luebke, Jennifer, Bryant, Camron D., Wolozin, Benjamin
Опубликовано в: Nat Neurosci (2017)

A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins

по Ruan, Qiu T., Yazdani, Neema, Blum, Benjamin C., Beierle, Jacob A., Lin, Weiwei, Coelho, Michal A., Fultz, Elissa K., Healy, Aidan F., Shahin, John R., Kandola, Amarpreet K., Luttik, Kimberly P., Zheng, Karen, Smith, Nathaniel J., Cheung, Justin, Mortazavi, Farzad, Apicco, Daniel J., Ragu Varman, Durairaj, Ramamoorthy, Sammanda, Ash, Peter E.A., Rosene, Douglas L., Emili, Andrew, Wolozin, Benjamin, Szumlinski, Karen K., Bryant, Camron D.
Опубликовано в: J Neurosci (2020)

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

по Pourhaghighi, Reza, Ash, Peter E. A., Phanse, Sadhna, Goebels, Florian, Hu, Lucas Z. M., Chen, Siwei, Zhang, Yingying, Wierbowski, Shayne D., Boudeau, Samantha, Moutaoufik, Mohamed T., Malty, Ramy H., Malolepsza, Edyta, Tsafou, Kalliopi, Nathan, Aparna, Cromar, Graham, Guo, Hongbo, Al Abdullatif, Ali, Apicco, Daniel J., Becker, Lindsay A., Gitler, Aaron D., Pulst, Stefan M., Youssef, Ahmed, Hekman, Ryan, Havugimana, Pierre C., White, Carl A., Blum, Benjamin C., Ratti, Antonia, Bryant, Camron D., Parkinson, John, Lage, Kasper, Babu, Mohan, Yu, Haiyuan, Bader, Gary D., Wolozin, Benjamin, Emili, Andrew
Опубликовано в: Cell Syst (2020)

C9ORF72 repeat expansions in cases with previously identified pathogenic mutations

по van Blitterswijk, Marka, Baker, Matthew C., DeJesus-Hernandez, Mariely, Ghidoni, Roberta, Benussi, Luisa, Finger, Elizabeth, Hsiung, Ging-Yuek R., Kelley, Brendan J., Murray, Melissa E., Rutherford, Nicola J., Brown, Patricia E., Ravenscroft, Thomas, Mullen, Bianca, Ash, Peter E.A., Bieniek, Kevin F., Hatanpaa, Kimmo J., Karydas, Anna, Wood, Elisabeth McCarty, Coppola, Giovanni, Bigio, Eileen H., Lippa, Carol, Strong, Michael J., Beach, Thomas G., Knopman, David S., Huey, Edward D., Mesulam, Marsel, Bird, Thomas, White, Charles L., Kertesz, Andrew, Geschwind, Dan H., Van Deerlin, Vivianna M., Petersen, Ronald C., Binetti, Giuliano, Miller, Bruce L., Petrucelli, Leonard, Wszolek, Zbigniew K., Boylan, Kevin B., Graff-Radford, Neill R., Mackenzie, Ian R., Boeve, Bradley F., Dickson, Dennis W., Rademakers, Rosa
Опубликовано 2013

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

по Hekman, Ryan M., Hume, Adam J., Goel, Raghuveera Kumar, Abo, Kristine M., Huang, Jessie, Blum, Benjamin C., Werder, Rhiannon B., Suder, Ellen L., Paul, Indranil, Phanse, Sadhna, Youssef, Ahmed, Alysandratos, Konstantinos D., Padhorny, Dzmitry, Ojha, Sandeep, Mora-Martin, Alexandra, Kretov, Dmitry, Ash, Peter E.A., Verma, Mamta, Zhao, Jian, Patten, J.J., Villacorta-Martin, Carlos, Bolzan, Dante, Perea-Resa, Carlos, Bullitt, Esther, Hinds, Anne, Tilston-Lunel, Andrew, Varelas, Xaralabos, Farhangmehr, Shaghayegh, Braunschweig, Ulrich, Kwan, Julian H., McComb, Mark, Basu, Avik, Saeed, Mohsan, Perissi, Valentina, Burks, Eric J., Layne, Matthew D., Connor, John H., Davey, Robert, Cheng, Ji-Xin, Wolozin, Benjamin L., Blencowe, Benjamin J., Wuchty, Stefan, Lyons, Shawn M., Kozakov, Dima, Cifuentes, Daniel, Blower, Michael, Kotton, Darrell N., Wilson, Andrew A., Mühlberger, Elke, Emili, Andrew
Опубликовано в: Mol Cell (2020)