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TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans

TDP-43 is a multifunctional nucleic acid binding protein linked to several neurodegenerative diseases including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia. To learn more about the normal biological and abnormal pathological role of this protein, we turned to Caenorhabditis elega...

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Detaylı Bibliyografya
Asıl Yazarlar: Vaccaro, Alexandra, Tauffenberger, Arnaud, Ash, Peter E. A., Carlomagno, Yari, Petrucelli, Leonard, Parker, J. Alex
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390363/
https://ncbi.nlm.nih.gov/pubmed/22792076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002806
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