Neurotoxic effects of TDP-43 overexpression in C. elegans

RNA-binding protein TDP-43 has been associated with multiple neurodegenerative diseases, including amyotrophic lateral sclerosis and frontotemporal lobar dementia. We have engineered pan-neuronal expression of human TDP-43 protein in Caenorhabditis elegans, with the goal of generating a convenient i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ash, Peter E.A., Zhang, Yong-Jie, Roberts, Christine M., Saldi, Tassa, Hutter, Harald, Buratti, Emanuele, Petrucelli, Leonard, Link, Christopher D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2010
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908471/
https://ncbi.nlm.nih.gov/pubmed/20530643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq230
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg