Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity

Dendritic mislocalization of microtubule associated protein tau is a hallmark of tauopathies, but the role of dendritic tau is unknown. We now report that tau interacts with the RNA-binding protein (RBP) TIA1 in brain tissue, and we present the brain-protein interactome network for TIA1. Analysis of...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Vanderweyde, Tara, Apicco, Daniel J., Youmans-Kidder, Katherine, Ash, Peter E.A., Cook, Casey, da Rocha, Edroaldo Lummertz, Jansen-West, Karen, Frame, Alissa A., Citro, Allison, Leszyk, John D., Ivanov, Pavel, Abisambra, Jose F., Steffen, Martin, Li, Hu, Petrucelli, Leonard, Wolozin, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325702/
https://ncbi.nlm.nih.gov/pubmed/27160897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.045
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