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TIA1 regulates the generation and response to toxic tau oligomers

RNA binding proteins (RBPs) are strongly linked to the pathophysiology of motor neuron diseases. Recent studies show that RBPs, such as TIA1, also contribute to the pathophysiology of tauopathy. RBPs co-localize with tau pathology, and reduction of TIA1 protects against tau-mediated neurodegeneratio...

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Détails bibliographiques
Publié dans:Acta Neuropathol
Auteurs principaux: Jiang, Lulu, Ash, Peter E. A., Maziuk, Brandon F., Ballance, Heather I., Boudeau, Samantha, Abdullatif, Ali Al, Orlando, Marcello, Petrucelli, Leonard, Ikezu, Tsuneya, Wolozin, Benjamin
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377165/
https://ncbi.nlm.nih.gov/pubmed/30465259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1937-5
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