Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach

per Artese, Anna, Costa, Giosuè, Ortuso, Francesco, Parrotta, Lucia, Alcaro, Stefano
Publicat a Molecules (2013)

Conformation and Stability of Intramolecular Telomeric G-Quadruplexes: Sequence Effects in the Loops

per Sattin, Giovanna, Artese, Anna, Nadai, Matteo, Costa, Giosuè, Parrotta, Lucia, Alcaro, Stefano, Palumbo, Manlio, Richter, Sara N.
Publicat 2013

Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations

per Moraca, Federica, Amato, Jussara, Ortuso, Francesco, Artese, Anna, Pagano, Bruno, Novellino, Ettore, Alcaro, Stefano, Parrinello, Michele, Limongelli, Vittorio
Publicat a Proc Natl Acad Sci U S A (2017)

Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations

per Rocca, Roberta, Moraca, Federica, Costa, Giosuè, Alcaro, Stefano, Distinto, Simona, Maccioni, Elias, Ortuso, Francesco, Artese, Anna, Parrotta, Lucia
Publicat a Molecules (2014)

In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes

per Rocca, Roberta, Moraca, Federica, Costa, Giosuè, Talarico, Carmine, Ortuso, Francesco, Da Ros, Silvia, Nicoletto, Giulia, Sissi, Claudia, Alcaro, Stefano, Artese, Anna
Publicat a ACS Med Chem Lett (2018)

Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics

per Rocca, Roberta, Palazzesi, Ferruccio, Amato, Jussara, Costa, Giosuè, Ortuso, Francesco, Pagano, Bruno, Randazzo, Antonio, Novellino, Ettore, Alcaro, Stefano, Moraca, Federica, Artese, Anna
Publicat a Sci Rep (2020)

Natural Products Extracted from Fungal Species as New Potential Anti-Cancer Drugs: A Structure-Based Drug Repurposing Approach Targeting HDAC7

per Maruca, Annalisa, Rocca, Roberta, Catalano, Raffaella, Mesiti, Francesco, Costa, Giosuè, Lanzillotta, Delia, Salatino, Alessandro, Ortuso, Francesco, Trapasso, Francesco, Alcaro, Stefano, Artese, Anna
Publicat a Molecules (2020)

Effect of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Polymorphism Leu-214 on Replication Capacity and Drug Susceptibility

per Puertas, Maria Carmen, Buzón, Maria Jose, Artese, Anna, Alcaro, Stefano, Menendez-Arias, Luis, Perno, Carlo Federico, Clotet, Bonaventura, Ceccherini-Silberstein, Francesca, Martinez-Picado, Javier
Publicat 2009

Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors

per Maruca, Annalisa, Lanzillotta, Delia, Rocca, Roberta, Lupia, Antonio, Costa, Giosuè, Catalano, Raffaella, Moraca, Federica, Gaudio, Eugenio, Ortuso, Francesco, Artese, Anna, Trapasso, Francesco, Alcaro, Stefano
Publicat a Molecules (2020)

Detecting and understanding genetic and structural features in HIV-1 B subtype V3 underlying HIV-1 co-receptor usage

per Chen, Mengjie, Svicher, Valentina, Artese, Anna, Costa, Giosuè, Alteri, Claudia, Ortuso, Francesco, Parrotta, Lucia, Liu, Yang, Liu, Chang, Perno, Carlo Federico, Alcaro, Stefano, Zhang, Jing
Publicat 2013

Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors

per Vernieri, Ermelinda, Gomez-Monterrey, Isabel, Milite, Ciro, Grieco, Paolo, Musella, Simona, Bertamino, Alessia, Scognamiglio, Ilaria, Alcaro, Stefano, Artese, Anna, Ortuso, Francesco, Novellino, Ettore, Sala, Marina, Campiglia, Pietro
Publicat 2013

In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

per Costa, Giosuè, Maruca, Annalisa, Rocca, Roberta, Ambrosio, Francesca Alessandra, Berrino, Emanuela, Carta, Fabrizio, Mesiti, Francesco, Salatino, Alessandro, Lanzillotta, Delia, Trapasso, Francesco, Artese, Anna, Alcaro, Stefano, Supuran, Claudiu T.
Publicat a Antioxidants (Basel) (2020)

Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses

per Artese, Anna, Svicher, Valentina, Costa, Giosuè, Salpini, Romina, Di Maio, Velia Chiara, Alkhatib, Mohammad, Ambrosio, Francesca Alessandra, Santoro, Maria Mercedes, Assaraf, Yehuda G., Alcaro, Stefano, Ceccherini-Silberstein, Francesca
Publicat a Drug Resist Updat (2020)

Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control

per Salpini, Romina, Alkhatib, Mohammad, Costa, Giosuè, Piermatteo, Lorenzo, Ambrosio, Francesca Alessandra, Di Maio, Velia Chiara, Scutari, Rossana, Duca, Leonardo, Berno, Giulia, Fabeni, Lavinia, Alcaro, Stefano, Ceccherini-Silberstein, Francesca, Artese, Anna, Svicher, Valentina
Publicat a J Antimicrob Chemother (2020)

Characterization and Structural Analysis of Novel Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involved in the Regulation of Resistance to Nonnucleoside I...

per Ceccherini-Silberstein, Francesca, Svicher, Valentina, Sing, Tobias, Artese, Anna, Santoro, Maria Mercedes, Forbici, Federica, Bertoli, Ada, Alcaro, Stefano, Palamara, Guido, d'Arminio Monforte , Antonella, Balzarini, Jan, Antinori , Andrea, Lengauer, Thomas, Perno, Carlo Federico
Publicat 2007

HCV Genotypes Are Differently Prone to the Development of Resistance to Linear and Macrocyclic Protease Inhibitors

per Cento, Valeria, Mirabelli, Carmen, Salpini, Romina, Dimonte, Salvatore, Artese, Anna, Costa, Giosuè, Mercurio, Fabio, Svicher, Valentina, Parrotta, Lucia, Bertoli, Ada, Ciotti, Marco, Di Paolo, Daniele, Sarrecchia, Cesare, Andreoni, Massimo, Alcaro, Stefano, Angelico, Mario, Perno, Carlo Federico, Ceccherini-Silberstein, Francesca
Publicat 2012

Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage

per Alteri, Claudia, Surdo, Matteo, Bellocchi, Maria Concetta, Saccomandi, Patrizia, Continenza, Fabio, Armenia, Daniele, Parrotta, Lucia, Carioti, Luca, Costa, Giosuè, Fourati, Slim, Di Santo, Fabiola, Scutari, Rossana, Barbaliscia, Silvia, Fedele, Valentina, Carta, Stefania, Balestra, Emanuela, Alcaro, Stefano, Marcelin, Anne Genevieve, Calvez, Vincent, Ceccherini-Silberstein, Francesca, Artese, Anna, Perno, Carlo Federico, Svicher, Valentina
Publicat a Antimicrob Agents Chemother (2015)