In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

The tumor-associated isoenzymes hCA IX and hCA XII catalyze the hydration of carbon dioxide to bicarbonate and protons. These isoforms are highly overexpressed in many types of cancer, where they contribute to the acidification of the tumor environment, promoting tumor cell invasion and metastasis....

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Udgivet i:Antioxidants (Basel)
Main Authors: Costa, Giosuè, Maruca, Annalisa, Rocca, Roberta, Ambrosio, Francesca Alessandra, Berrino, Emanuela, Carta, Fabrizio, Mesiti, Francesco, Salatino, Alessandro, Lanzillotta, Delia, Trapasso, Francesco, Artese, Anna, Alcaro, Stefano, Supuran, Claudiu T.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555330/
https://ncbi.nlm.nih.gov/pubmed/32825614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9090775
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