Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach

Por Artese, Anna, Costa, Giosuè, Ortuso, Francesco, Parrotta, Lucia, Alcaro, Stefano
Publicado no Molecules (2013)

Conformation and Stability of Intramolecular Telomeric G-Quadruplexes: Sequence Effects in the Loops

Por Sattin, Giovanna, Artese, Anna, Nadai, Matteo, Costa, Giosuè, Parrotta, Lucia, Alcaro, Stefano, Palumbo, Manlio, Richter, Sara N.
Publicado em 2013

Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations

Por Moraca, Federica, Amato, Jussara, Ortuso, Francesco, Artese, Anna, Pagano, Bruno, Novellino, Ettore, Alcaro, Stefano, Parrinello, Michele, Limongelli, Vittorio
Publicado no Proc Natl Acad Sci U S A (2017)

Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations

Por Rocca, Roberta, Moraca, Federica, Costa, Giosuè, Alcaro, Stefano, Distinto, Simona, Maccioni, Elias, Ortuso, Francesco, Artese, Anna, Parrotta, Lucia
Publicado no Molecules (2014)

In Silico Identification of Piperidinyl-amine Derivatives as Novel Dual Binders of Oncogene c-myc/c-Kit G-quadruplexes

Por Rocca, Roberta, Moraca, Federica, Costa, Giosuè, Talarico, Carmine, Ortuso, Francesco, Da Ros, Silvia, Nicoletto, Giulia, Sissi, Claudia, Alcaro, Stefano, Artese, Anna
Publicado no ACS Med Chem Lett (2018)

Folding intermediate states of the parallel human telomeric G-quadruplex DNA explored using Well-Tempered Metadynamics

Por Rocca, Roberta, Palazzesi, Ferruccio, Amato, Jussara, Costa, Giosuè, Ortuso, Francesco, Pagano, Bruno, Randazzo, Antonio, Novellino, Ettore, Alcaro, Stefano, Moraca, Federica, Artese, Anna
Publicado no Sci Rep (2020)

Natural Products Extracted from Fungal Species as New Potential Anti-Cancer Drugs: A Structure-Based Drug Repurposing Approach Targeting HDAC7

Por Maruca, Annalisa, Rocca, Roberta, Catalano, Raffaella, Mesiti, Francesco, Costa, Giosuè, Lanzillotta, Delia, Salatino, Alessandro, Ortuso, Francesco, Trapasso, Francesco, Alcaro, Stefano, Artese, Anna
Publicado no Molecules (2020)

Effect of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Polymorphism Leu-214 on Replication Capacity and Drug Susceptibility

Por Puertas, Maria Carmen, Buzón, Maria Jose, Artese, Anna, Alcaro, Stefano, Menendez-Arias, Luis, Perno, Carlo Federico, Clotet, Bonaventura, Ceccherini-Silberstein, Francesca, Martinez-Picado, Javier
Publicado em 2009

Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors

Por Maruca, Annalisa, Lanzillotta, Delia, Rocca, Roberta, Lupia, Antonio, Costa, Giosuè, Catalano, Raffaella, Moraca, Federica, Gaudio, Eugenio, Ortuso, Francesco, Artese, Anna, Trapasso, Francesco, Alcaro, Stefano
Publicado no Molecules (2020)

Detecting and understanding genetic and structural features in HIV-1 B subtype V3 underlying HIV-1 co-receptor usage

Por Chen, Mengjie, Svicher, Valentina, Artese, Anna, Costa, Giosuè, Alteri, Claudia, Ortuso, Francesco, Parrotta, Lucia, Liu, Yang, Liu, Chang, Perno, Carlo Federico, Alcaro, Stefano, Zhang, Jing
Publicado em 2013

Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors

Por Vernieri, Ermelinda, Gomez-Monterrey, Isabel, Milite, Ciro, Grieco, Paolo, Musella, Simona, Bertamino, Alessia, Scognamiglio, Ilaria, Alcaro, Stefano, Artese, Anna, Ortuso, Francesco, Novellino, Ettore, Sala, Marina, Campiglia, Pietro
Publicado em 2013

In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

Por Costa, Giosuè, Maruca, Annalisa, Rocca, Roberta, Ambrosio, Francesca Alessandra, Berrino, Emanuela, Carta, Fabrizio, Mesiti, Francesco, Salatino, Alessandro, Lanzillotta, Delia, Trapasso, Francesco, Artese, Anna, Alcaro, Stefano, Supuran, Claudiu T.
Publicado no Antioxidants (Basel) (2020)

Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses

Por Artese, Anna, Svicher, Valentina, Costa, Giosuè, Salpini, Romina, Di Maio, Velia Chiara, Alkhatib, Mohammad, Ambrosio, Francesca Alessandra, Santoro, Maria Mercedes, Assaraf, Yehuda G., Alcaro, Stefano, Ceccherini-Silberstein, Francesca
Publicado no Drug Resist Updat (2020)

Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control

Por Salpini, Romina, Alkhatib, Mohammad, Costa, Giosuè, Piermatteo, Lorenzo, Ambrosio, Francesca Alessandra, Di Maio, Velia Chiara, Scutari, Rossana, Duca, Leonardo, Berno, Giulia, Fabeni, Lavinia, Alcaro, Stefano, Ceccherini-Silberstein, Francesca, Artese, Anna, Svicher, Valentina
Publicado no J Antimicrob Chemother (2020)

Characterization and Structural Analysis of Novel Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involved in the Regulation of Resistance to Nonnucleoside I...

Por Ceccherini-Silberstein, Francesca, Svicher, Valentina, Sing, Tobias, Artese, Anna, Santoro, Maria Mercedes, Forbici, Federica, Bertoli, Ada, Alcaro, Stefano, Palamara, Guido, d'Arminio Monforte , Antonella, Balzarini, Jan, Antinori , Andrea, Lengauer, Thomas, Perno, Carlo Federico
Publicado em 2007

HCV Genotypes Are Differently Prone to the Development of Resistance to Linear and Macrocyclic Protease Inhibitors

Por Cento, Valeria, Mirabelli, Carmen, Salpini, Romina, Dimonte, Salvatore, Artese, Anna, Costa, Giosuè, Mercurio, Fabio, Svicher, Valentina, Parrotta, Lucia, Bertoli, Ada, Ciotti, Marco, Di Paolo, Daniele, Sarrecchia, Cesare, Andreoni, Massimo, Alcaro, Stefano, Angelico, Mario, Perno, Carlo Federico, Ceccherini-Silberstein, Francesca
Publicado em 2012

Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage

Por Alteri, Claudia, Surdo, Matteo, Bellocchi, Maria Concetta, Saccomandi, Patrizia, Continenza, Fabio, Armenia, Daniele, Parrotta, Lucia, Carioti, Luca, Costa, Giosuè, Fourati, Slim, Di Santo, Fabiola, Scutari, Rossana, Barbaliscia, Silvia, Fedele, Valentina, Carta, Stefania, Balestra, Emanuela, Alcaro, Stefano, Marcelin, Anne Genevieve, Calvez, Vincent, Ceccherini-Silberstein, Francesca, Artese, Anna, Perno, Carlo Federico, Svicher, Valentina
Publicado no Antimicrob Agents Chemother (2015)