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Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach

The G-quadruplex DNA structures are mainly present at the terminal portion of telomeres and can be stabilized by ligands able to recognize them in a specific manner. The recognition process is usually related to the inhibition of the enzyme telomerase indirectly involved and over-expressed in a high...

詳細記述

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書誌詳細
出版年:Molecules
主要な著者: Artese, Anna, Costa, Giosuè, Ortuso, Francesco, Parrotta, Lucia, Alcaro, Stefano
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270229/
https://ncbi.nlm.nih.gov/pubmed/24084014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181012051
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