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Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach
The G-quadruplex DNA structures are mainly present at the terminal portion of telomeres and can be stabilized by ligands able to recognize them in a specific manner. The recognition process is usually related to the inhibition of the enzyme telomerase indirectly involved and over-expressed in a high...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6270229/ https://ncbi.nlm.nih.gov/pubmed/24084014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181012051 |
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