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Conformation and Stability of Intramolecular Telomeric G-Quadruplexes: Sequence Effects in the Loops
Telomeres are guanine-rich sequences that protect the ends of chromosomes. These regions can fold into G-quadruplex structures and their stabilization by G-quadruplex ligands has been employed as an anticancer strategy. Genetic analysis in human telomeres revealed extensive allelic variation restric...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867476/ https://ncbi.nlm.nih.gov/pubmed/24367632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084113 |
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