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The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids()

BACKGROUND: G-quadruplexes (G4s) are four-stranded nucleic acid structures that form in G-rich sequences. Nucleolin (NCL) is a cellular protein reported for its functions upon G4 recognition, such as induction of neurodegenerative diseases, tumor and virus mechanisms activation. We here aimed at def...

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Bibliographic Details
Published in:Biochim Biophys Acta Gen Subj
Main Authors: Lago, Sara, Tosoni, Elena, Nadai, Matteo, Palumbo, Manlio, Richter, Sara N.
Format: Artigo
Language:Inglês
Published: The Author(s). Published by Elsevier B.V. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466061/
https://ncbi.nlm.nih.gov/pubmed/27913192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.11.036
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