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Detecting and understanding genetic and structural features in HIV-1 B subtype V3 underlying HIV-1 co-receptor usage

Motivation: To define V3 genetic elements and structural features underlying different HIV-1 co-receptor usage in vivo. Results: By probabilistically modeling mutations in the viruses isolated from HIV-1 B subtype patients, we present a unique statistical procedure that would first identify V3 deter...

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Autors principals: Chen, Mengjie, Svicher, Valentina, Artese, Anna, Costa, Giosuè, Alteri, Claudia, Ortuso, Francesco, Parrotta, Lucia, Liu, Yang, Liu, Chang, Perno, Carlo Federico, Alcaro, Stefano, Zhang, Jing
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570207/
https://ncbi.nlm.nih.gov/pubmed/23297034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt002
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