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A class of carbonic anhydrase IX/XII – selective carboxylate inhibitors
A small series of 2,4-dioxothiazolidinyl acetic acids was prepared from thiourea, chloroacetic acid, aromatic aldehydes, and ethyl-2-bromoacetate. They were assayed for the inhibition of four physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isoforms of human (h) origin, the cytosolic hCA...
Gardado en:
| Publicado en: | J Enzyme Inhib Med Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7006686/ https://ncbi.nlm.nih.gov/pubmed/31967484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1715388 |
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