A class of carbonic anhydrase IX/XII – selective carboxylate inhibitors

A small series of 2,4-dioxothiazolidinyl acetic acids was prepared from thiourea, chloroacetic acid, aromatic aldehydes, and ethyl-2-bromoacetate. They were assayed for the inhibition of four physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isoforms of human (h) origin, the cytosolic hCA...

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Bibliografiset tiedot
Julkaisussa:J Enzyme Inhib Med Chem
Päätekijät: Alhameed, Rakia Abd, Berrino, Emanuela, Almarhoon, Zainab, El-Faham, Ayman, Supuran, Claudiu T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2020
Aiheet:
Short Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006686/
https://ncbi.nlm.nih.gov/pubmed/31967484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1715388
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