Breakthrough in GPCR Crystallography and its Impact on Computer-Aided Drug Design

Por Ciancetta, Antonella, Jacobson, Kenneth A.
Publicado no Methods Mol Biol (2018)

Mathematical Simulation of Muscle Cross-Bridge Cycle and Force-Velocity Relationship

Por Chin, Leslie, Yue, Pengtao, Feng, James J., Seow, Chun Y.
Publicado em 2006

Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial

Por Coleman, Robert L, Oza, Amit M, Lorusso, Domenica, Aghajanian, Carol, Oaknin, Ana, Dean, Andrew, Colombo, Nicoletta, Weberpals, Johanne I, Clamp, Andrew, Scambia, Giovanni, Leary, Alexandra, Holloway, Robert W, Gancedo, Margarita Amenedo, Fong, Peter C, Goh, Jeffrey C, O’Malley, David M, Armstrong, Deborah K, Garcia-Donas, Jesus, Swisher, Elizabeth M, Floquet, Anne, Konecny, Gottfried E, McNeish, Iain A, Scott, Clare L, Cameron, Terri, Maloney, Lara, Isaacson, Jeff, Goble, Sandra, Grace, Caroline, Harding, Thomas C, Raponi, Mitch, Sun, James, Lin, Kevin K, Giordano, Heidi, Ledermann, Jonathan A
Publicado no Lancet (2017)

Poster Session B

Publicado no Mol Cell Proteomics (2019)

Computational and Experimental Studies of ADP-Ribosylation

Por Hammond, Robert G., Tan, Xuan, Chan, Matthew, Goel, Anupam, Johnson, Margaret A.
Publicado no Poly(ADP-Ribose) Polymerase (2017)

Complete Nucleotide Sequence and Organization of the Atrazine Catabolic Plasmid pADP-1 from Pseudomonas sp. Strain ADP

Por Martinez, Betsy, Tomkins, Jeffrey, Wackett, Lawrence P., Wing, Rod, Sadowsky, Michael J.
Publicado em 2001

Adaptive Dynamic Programming-Based Multi-Sensor Scheduling for Collaborative Target Tracking in Energy Harvesting Wireless Sensor Networks

Por Liu, Fen, Xiao, Wendong, Chen, Shuai, Jiang, Chengpeng
Publicado no Sensors (Basel) (2018)

Identification of a Different Agonist-Binding Site and Activation Mechanism of the Human P2Y(1) Receptor

Por Li, Yang, Yin, Can, Liu, Pi, Li, Dongmei, Lin, Jianping
Publicado no Sci Rep (2017)

Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier

Por Shihao Yao, Qiuzi Yi, Boyuan Ma, Xiaoting Mao, Ye Chen, Min-Xin Guan, Xiaohui Cang
Publicado em 2022-01-01

Exhaustion of Skeletal Muscle Fibers Within Seconds: Incorporating Phosphate Kinetics Into a Hill-Type Model

Por Robert Rockenfeller, Michael Günther, Michael Günther, Norman Stutzig, Daniel F. B. Haeufle, Tobias Siebert, Syn Schmitt, Kay Leichsenring, Markus Böl, Thomas Götz
Publicado em 2020-05-01

The Father, Son and Cholix Toxin: The Third Member of the DT Group Mono-ADP-Ribosyltransferase Toxin Family

Por Lugo, Miguel R., Merrill, A. Rod
Publicado no Toxins (Basel) (2015)

Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers...

Por Zoll, Joffrey, Bouitbir, Jamal, Sirvent, Pascal, Klein, Alexis, Charton, Antoine, Jimenez, Liliana, Péronnet, François R, Geny, Bernard, Richard, Ruddy
Publicado no Drug Des Devel Ther (2015)

ATP Transport through VDAC and the VDAC–Tubulin Complex Probed by Equilibrium and Nonequilibrium MD Simulations

Por Noskov, Sergei Yu., Rostovtseva, Tatiana K., Bezrukov, Sergey M.
Publicado no Biochemistry (2013)

In Silico Screening Identifies a Novel Potential PARP1 Inhibitor Targeting Synthetic Lethality in Cancer Treatment

Por Li, Jian, Zhou, Nan, Cai, Peiling, Bao, Jinku
Publicado no Int J Mol Sci (2016)

Understanding the Phosphorylation Mechanism by Using Quantum Chemical Calculations and Molecular Dynamics Simulations

Por Han, Weiwei, Zhu, Jingxuan, Wang, Song, Xu, Dong
Publicado no J Phys Chem B (2016)

AutoGrow4: an open-source genetic algorithm for de novo drug design and lead optimization

Por Spiegel, Jacob O., Durrant, Jacob D.
Publicado no J Cheminform (2020)

Mitochondrial Energetics, pH Regulation, and Ion Dynamics: A Computational-Experimental Approach

Por Wei, An-Chi, Aon, Miguel A., O'Rourke, Brian, Winslow, Raimond L., Cortassa, Sonia
Publicado em 2011

Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking

Por Schuller, Marion, Correy, Galen J., Gahbauer, Stefan, Fearon, Daren, Wu, Taiasean, Díaz, Roberto Efraín, Young, Iris D., Martins, Luan Carvalho, Smith, Dominique H., Schulze-Gahmen, Ursula, Owens, Tristan W., Deshpande, Ishan, Merz, Gregory E., Thwin, Aye C., Biel, Justin T., Peters, Jessica K., Moritz, Michelle, Herrera, Nadia, Kratochvil, Huong T., Aimon, Anthony, Bennett, James M., Neto, Jose Brandao, Cohen, Aina E., Dias, Alexandre, Douangamath, Alice, Dunnett, Louise, Fedorov, Oleg, Ferla, Matteo P., Fuchs, Martin, Gorrie-Stone, Tyler J., Holton, James M., Johnson, Michael G., Krojer, Tobias, Meigs, George, Powell, Ailsa J., Rangel, Victor L, Russi, Silvia, Skyner, Rachael E., Smith, Clyde A., Soares, Alexei S., Wierman, Jennifer L., Zhu, Kang, Jura, Natalia, Ashworth, Alan, Irwin, John, Thompson, Michael C., Gestwicki, Jason E., von Delft, Frank, Shoichet, Brian K., Fraser, James S., Ahel, Ivan
Publicado no bioRxiv (2020)

A Kinetic Model Describing the Processivity of Myosin-V

Por Skau, Karl I., Hoyle, Rebecca B., Turner, Matthew S.
Publicado em 2006

Use of Protein Kinase Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors

Por Puhl-Rubio, Ana C., Stashko, Michael A., Wang, Huanchen, Hardy, P. Brian, Tyagi, Vikas, Li, Bing, Wang, Xiaodong, Kireev, Dmitri, Jessen, Henning J., Frye, Stephen V., Shears, Stephen B., Pearce, Kenneth H.
Publicado no SLAS Discov (2018)