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Breakthrough in GPCR Crystallography and its Impact on Computer-Aided Drug Design
Recent crystallographic structures of G protein-coupled receptors (GPCRs) have greatly advanced our understanding of the recognition of their diverse agonist and antagonist ligands. We illustrate here how this applies to A(2A) adenosine receptors (ARs) and to P2Y(1) and P2Y(12) receptors (P2YRs) for...
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| Publicat a: | Methods Mol Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859332/ https://ncbi.nlm.nih.gov/pubmed/29188558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7465-8_3 |
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