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Breakthrough in GPCR Crystallography and its Impact on Computer-Aided Drug Design
Recent crystallographic structures of G protein-coupled receptors (GPCRs) have greatly advanced our understanding of the recognition of their diverse agonist and antagonist ligands. We illustrate here how this applies to A(2A) adenosine receptors (ARs) and to P2Y(1) and P2Y(12) receptors (P2YRs) for...
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| 出版年: | Methods Mol Biol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859332/ https://ncbi.nlm.nih.gov/pubmed/29188558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7465-8_3 |
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