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Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier

The ADP/ATP carrier (AAC) is crucial for mitochondrial functions by importing ADP and exporting ATP across the inner mitochondrial membrane. However, the mechanism of highly specific ADP recognition and transport by AAC remains largely elusive. In this work, spontaneous ADP binding process to the gr...

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Autores principales: Shihao Yao, Qiuzi Yi, Boyuan Ma, Xiaoting Mao, Ye Chen, Min-Xin Guan, Xiaohui Cang
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2022-01-01
Colección:Computational and Structural Biotechnology Journal
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2001037022001076
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