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ATP Transport through VDAC and the VDAC–Tubulin Complex Probed by Equilibrium and Nonequilibrium MD Simulations

Voltage-dependent anion channel (VDAC), the major channel of the mitochondrial outer membrane, serves as a principal pathway for ATP, ADP, and other respiratory substrates across this membrane. Using umbrella-sampling simulations, we established the thermodynamic and kinetic components governing ATP...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Noskov, Sergei Yu., Rostovtseva, Tatiana K., Bezrukov, Sergey M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259721/
https://ncbi.nlm.nih.gov/pubmed/24245503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4011495
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