Use of Protein Kinase Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors

Inositol hexakisphosphate kinases (IP6Ks) regulate a myriad of cellular processes, not only through their catalytic activity which synthesizes InsP(7), a multifunctional inositol pyrophosphate signaling molecule, but also through protein-protein interactions. To further study the enzymatic function...

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Publicado no:SLAS Discov
Main Authors: Puhl-Rubio, Ana C., Stashko, Michael A., Wang, Huanchen, Hardy, P. Brian, Tyagi, Vikas, Li, Bing, Wang, Xiaodong, Kireev, Dmitri, Jessen, Henning J., Frye, Stephen V., Shears, Stephen B., Pearce, Kenneth H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148399/
https://ncbi.nlm.nih.gov/pubmed/29842835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218775323
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