Use of Protein Kinase Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors

Inositol hexakisphosphate kinases (IP6Ks) regulate a myriad of cellular processes, not only through their catalytic activity which synthesizes InsP(7), a multifunctional inositol pyrophosphate signaling molecule, but also through protein-protein interactions. To further study the enzymatic function...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:SLAS Discov
Prif Awduron: Puhl-Rubio, Ana C., Stashko, Michael A., Wang, Huanchen, Hardy, P. Brian, Tyagi, Vikas, Li, Bing, Wang, Xiaodong, Kireev, Dmitri, Jessen, Henning J., Frye, Stephen V., Shears, Stephen B., Pearce, Kenneth H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148399/
https://ncbi.nlm.nih.gov/pubmed/29842835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218775323
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