Human cancers converge at the HIF-2α oncogenic axis

Por Franovic, Aleksandra, Holterman, Chet E., Payette, Josianne, Lee, Stephen
Publicado em 2009

A single evolutionary innovation drives the deep evolution of symbiotic N(2)-fixation in angiosperms

Por Werner, Gijsbert D. A., Cornwell, William K., Sprent, Janet I., Kattge, Jens, Kiers, E. Toby
Publicado em 2014

Characterizing sleep spindles in 11,630 individuals from the National Sleep Research Resource

Por Purcell, S. M., Manoach, D. S., Demanuele, C., Cade, B. E., Mariani, S., Cox, R., Panagiotaropoulou, G., Saxena, R., Pan, J. Q., Smoller, J. W., Redline, S., Stickgold, R.
Publicado no Nat Commun (2017)

Chromatin interactions and expression quantitative trait loci reveal genetic drivers of multimorbidities

Por Fadason, Tayaza, Schierding, William, Lumley, Thomas, O’Sullivan, Justin M.
Publicado no Nat Commun (2018)

Population and individual-specific regulatory variation in Sardinia

Por Pala, M., Zappala, Z., Marongiu, M., Li, X., Davis, J.R., Cusano, R., Crobu, F., Kukurba, K.R., Gloudemans, M.J., Reinier, F., Berutti, R., Piras, M.G., Mulas, A., Zoledziewska, M., Marongiu, M., Sorokin, E.P., Hess, G.T., Smith, K.S., Busonero, F., Maschio, A., Steri, M., Sidore, C., Sanna, S., Fiorillo, E., Bassik, M.C., Sawcer, S.J., Battle, A.J., Novembre, J., Jones, C., Angius, A., Abecasis, G.R., Schlessinger, D., Cucca, F., Montgomery, S.B.
Publicado no Nat Genet (2017)

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Por Haworth, Simon, Shapland, Chin Yang, Hayward, Caroline, Prins, Bram P., Felix, Janine F., Medina-Gomez, Carolina, Rivadeneira, Fernando, Wang, Carol, Ahluwalia, Tarunveer S., Vrijheid, Martine, Guxens, Mònica, Sunyer, Jordi, Tachmazidou, Ioanna, Walter, Klaudia, Iotchkova, Valentina, Jackson, Andrew, Cleal, Louise, Huffmann, Jennifer, Min, Josine L., Sass, Lærke, Timmers, Paul R. H. J., Davey Smith, George, Fisher, Simon E., Wilson, James F., Cole, Tim J., Fernandez-Orth, Dietmar, Bønnelykke, Klaus, Bisgaard, Hans, Pennell, Craig E., Jaddoe, Vincent W. V., Dedoussis, George, Timpson, Nicholas, Zeggini, Eleftheria, Vitart, Veronique, St Pourcain, Beate
Publicado no Nat Commun (2019)

Rare mutations in the complement regulatory gene CSMD1 are associated with male and female infertility

Por Lee, Arthur S., Rusch, Jannette, Lima, Ana C., Usmani, Abul, Huang, Ni, Lepamets, Maarja, Vigh-Conrad, Katinka A., Worthington, Ronald E., Mägi, Reedik, Wu, Xiaobo, Aston, Kenneth I., Atkinson, John P., Carrell, Douglas T., Hess, Rex A., O’Bryan, Moira K., Conrad, Donald F.
Publicado no Nat Commun (2019)

The evolution and population diversity of human-specific segmental duplications

Por Dennis, Megan Y., Harshman, Lana, Nelson, Bradley J., Penn, Osnat, Cantsilieris, Stuart, Huddleston, John, Antonacci, Francesca, Penewit, Kelsi, Denman, Laura, Raja, Archana, Baker, Carl, Mark, Kenneth, Malig, Maika, Janke, Nicolette, Espinoza, Claudia, Stessman, Holly A.F., Nuttle, Xander, Hoekzema, Kendra, Lindsay-Graves, Tina A., Wilson, Richard K., Eichler, Evan E.
Publicado no Nat Ecol Evol (2017)

Mapping cis- and trans-regulatory effects across multiple tissues in twins

Por Grundberg, Elin, Small, Kerrin S., Hedman, Åsa K., Nica, Alexandra C., Buil, Alfonso, Keildson, Sarah, Bell, Jordana T., Yang, Tsun-Po, Meduri, Eshwar, Barrett, Amy, Nisbett, James, Sekowska, Magdalena, Wilk, Alicja, Shin, So-Youn, Glass, Daniel, Travers, Mary, Min, Josine L., Ring, Sue, Ho, Karen, Thorleifsson, Gudmar, Kong, Augustine, Thorsteindottir, Unnur, Ainali, Chrysanthi, Dimas, Antigone S., Hassanali, Neelam, Ingle, Catherine, Knowles, David, Krestyaninova, Maria, Lowe, Christopher E., Di Meglio, Paola, Montgomery, Stephen B., Parts, Leopold, Potter, Simon, Surdulescu, Gabriela, Tsaprouni, Loukia, Tsoka, Sophia, Bataille, Veronique, Durbin, Richard, Nestle, Frank O., O’Rahilly, Stephen, Soranzo, Nicole, Lindgren, Cecilia M., Zondervan, Krina T., Ahmadi, Kourosh R., Schadt, Eric E., Stefansson, Kari, Smith, George Davey, McCarthy, Mark I., Deloukas, Panos, Dermitzakis, Emmanouil T., Spector, Tim D.
Publicado em 2012

Genetic determinants of co-accessible chromatin regions in activated T cells across humans

Por Gate, Rachel E., Cheng, Christine S., Aiden, Aviva P., Siba, Atsede, Tabaka, Marcin, Lituiev, Dmytro, Machol, Ido, Gordon, M. Grace, Subramaniam, Meena, Shamim, Muhammad, Hougen, Kendrick L., Wortman, Ivo, Huang, Su-Chen, Durand, Neva C., Feng, Ting, De Jager, Philip L., Chang, Howard Y., Aiden, Erez Lieberman, Benoist, Christophe, Beer, Michael A., Ye, Chun J., Regev, Aviv
Publicado no Nat Genet (2018)

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

Por Morrow, James J., Bayles, Ian, Funnell, Alister PW, Miller, Tyler E., Saiakhova, Alina, Lizardo, Michael M., Bartels, Cynthia F., Kapteijn, Maaike Y., Hung, Stevephen, Mendoza, Arnulfo, Dhillon, Gursimran, Chee, Daniel R., Myers, Jay T., Allen, Frederick, Gambarotti, Marco, Righi, Alberto, DiFeo, Analisa, Rubin, Brian P., Huang, Alex Y., Meltzer, Paul S., Helman, Lee J., Picci, Piero, Versteeg, Henri, Stamatoyannopolus, John, Khanna, Chand, Scacheri, Peter C.
Publicado no Nat Med (2018)

Systematic identification of trans-eQTLs as putative drivers of known disease associations

Por Westra, Harm-Jan, Peters, Marjolein J., Esko, Tõnu, Yaghootkar, Hanieh, Schurmann, Claudia, Kettunen, Johannes, Christiansen, Mark W., Fairfax, Benjamin P., Schramm, Katharina, Powell, Joseph E., Zhernakova, Alexandra, Zhernakova, Daria V, Veldink, Jan H., Van den Berg, Leonard H., Karjalainen, Juha, Withoff, Sebo, Uitterlinden, André G., Hofman, Albert, Rivadeneira, Fernando, Hoen, Peter A C 't, Reinmaa, Eva, Fischer, Krista, Nelis, Mari, Milani, Lili, Melzer, David, Ferrucci, Luigi, Singleton, Andrew B., Hernandez, Dena G., Nalls, Michael A., Homuth, Georg, Nauck, Matthias, Radke, Dörte, Völker, Uwe, Perola, Markus, Salomaa, Veikko, Brody, Jennifer, Suchy-Dicey, Astrid, Gharib, Sina A., Enquobahrie, Daniel A., Lumley, Thomas, Montgomery, Grant W., Makino, Seiko, Prokisch, Holger, Herder, Christian, Roden, Michael, Grallert, Harald, Meitinger, Thomas, Strauch, Konstantin, Li, Yang, Jansen, Ritsert C., Visscher, Peter M., Knight, Julian C., Psaty, Bruce M., Ripatti, Samuli, Teumer, Alexander, Frayling, Timothy M., Metspalu, Andres, van Meurs, Joyce B.J., Franke, Lude
Publicado em 2013

Hologenomic adaptations underlying the evolution of sanguivory in the common vampire bat

Por Mendoza, M. Lisandra Zepeda, Xiong, Zijun, Escalera-Zamudio, Marina, Runge, Anne Kathrine, Thézé, Julien, Streicker, Daniel, Frank, Hannah K., Loza-Rubio, Elizabeth, Liu, Shengmao, Ryder, Oliver A., Castruita, Jose Alfredo Samaniego, Katzourakis, Aris, Pacheco, George, Taboada, Blanca, Löber, Ulrike, Pybus, Oliver G., Li, Yang, Rojas-Anaya, Edith, Bohmann, Kristine, Baez, Aldo Carmona, Arias, Carlos F., Liu, Shiping, Greenwood, Alex D., Bertelsen, Mads F., White, Nicole E., Bunce, Michael, Zhang, Guojie, Sicheritz-Pontén, Thomas, Gilbert, M. Thomas P.
Publicado no Nat Ecol Evol (2018)

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

Por Barban, Nicola, Jansen, Rick, de Vlaming, Ronald, Vaez, Ahmad, Mandemakers, Jornt J., Tropf, Felix C., Shen, Xia, Wilson, James F., Chasman, Daniel I., Nolte, Ilja M., Tragante, Vinicius, van der Laan, Sander W., Perry, John R. B., Kong, Augustine, Ahluwalia, Tarunveer, Albrecht, Eva, Yerges-Armstrong, Laura, Atzmon, Gil, Auro, Kirsi, Ayers, Kristin, Bakshi, Andrew, Ben-Avraham, Danny, Berger, Klaus, Bergman, Aviv, Bertram, Lars, Bielak, Lawrence F., Bjornsdottir, Gyda, Bonder, Marc Jan, Broer, Linda, Bui, Minh, Barbieri, Caterina, Cavadino, Alana, Chavarro, Jorge E, Turman, Constance, Concas, Maria Pina, Cordell, Heather J., Davies, Gail, Eibich, Peter, Eriksson, Nicholas, Esko, Tõnu, Eriksson, Joel, Falahi, Fahimeh, Felix, Janine F., Fontana, Mark Alan, Franke, Lude, Gandin, Ilaria, Gaskins, Audrey J., Gieger, Christian, Gunderson, Erica P., Guo, Xiuqing, Hayward, Caroline, He, Chunyan, Hofer, Edith, Huang, Hongyan, Joshi, Peter K., Kanoni, Stavroula, Karlsson, Robert, Kiechl, Stefan, Kifley, Annette, Kluttig, Alexander, Kraft, Peter, Lagou, Vasiliki, Lecoeur, Cecile, Lahti, Jari, Li-Gao, Ruifang, Lind, Penelope A., Liu, Tian, Makalic, Enes, Mamasoula, Crysovalanto, Matteson, Lindsay, Mbarek, Hamdi, McArdle, Patrick F., McMahon, George, Meddens, S. Fleur W., Mihailov, Evelin, Miller, Mike, Missmer, Stacey A., Monnereau, Claire, van der Most, Peter J., Myhre, Ronny, Nalls, Mike A., Nutile, Teresa, Panagiota, Kalafati Ioanna, Porcu, Eleonora, Prokopenko, Inga, Rajan, Kumar B., Rich-Edwards, Janet, Rietveld, Cornelius A., Robino, Antonietta, Rose, Lynda M., Rueedi, Rico, Ryan, Kathy, Saba, Yasaman, Schmidt, Daniel, Smith, Jennifer A., Stolk, Lisette, Streeten, Elizabeth, Tonjes, Anke, Thorleifsson, Gudmar, Ulivi, Sheila, Wedenoja, Juho, Wellmann, Juergen, Willeit, Peter, Yao, Jie, Yengo, Loic, Zhao, Jing Hua, Zhao, Wei, Zhernakova, Daria V., Amin, Najaf, Andrews, Howard, Balkau, Beverley, Barzilai, Nir, Bergmann, Sven, Biino, Ginevra, Bisgaard, Hans, Bønnelykke, Klaus, Boomsma, Dorret I., Buring, Julie E., Campbell, Harry, Cappellani, Stefania, Ciullo, Marina, Cox, Simon R., Cucca, Francesco, Daniela, Toniolo, Davey-Smith, George, Deary, Ian J., Dedoussis, George, Deloukas, Panos, van Duijn, Cornelia M., de Geus, Eco JC., Eriksson, Johan G., Evans, Denis A., Faul, Jessica D., Felicita, Sala Cinzia, Froguel, Philippe, Gasparini, Paolo, Girotto, Giorgia, Grabe, Hans-Jörgen, Greiser, Karin Halina, Groenen, Patrick J.F., de Haan, Hugoline G., Haerting, Johannes, Harris, Tamara B., Heath, Andrew C., Heikkilä, Kauko, Hofman, Albert, Homuth, Georg, Holliday, Elizabeth G, Hopper, John, Hypponen, Elina, Jacobsson, Bo, Jaddoe, Vincent W. V., Johannesson, Magnus, Jugessur, Astanand, Kähönen, Mika, Kajantie, Eero, Kardia, Sharon L.R., Keavney, Bernard, Kolcic, Ivana, Koponen, Päivikki, Kovacs, Peter, Kronenberg, Florian, Kutalik, Zoltan, La Bianca, Martina, Lachance, Genevieve, Iacono, William, Lai, Sandra, Lehtimäki, Terho, Liewald, David C, Lindgren, Cecilia, Liu, Yongmei, Luben, Robert, Lucht, Michael, Luoto, Riitta, Magnus, Per, Magnusson, Patrik K.E., Martin, Nicholas G., McGue, Matt, McQuillan, Ruth, Medland, Sarah E., Meisinger, Christa, Mellström, Dan, Metspalu, Andres, Michela, Traglia, Milani, Lili, Mitchell, Paul, Montgomery, Grant W., Mook-Kanamori, Dennis, de Mutsert, Renée, Nohr, Ellen A, Ohlsson, Claes, Olsen, Jørn, Ong, Ken K., Paternoster, Lavinia, Pattie, Alison, Penninx, Brenda WJH, Perola, Markus, Peyser, Patricia A., Pirastu, Mario, Polasek, Ozren, Power, Chris, Kaprio, Jaakko, Raffel, Leslie J., Räikkönen, Katri, Raitakari, Olli, Ridker, Paul M., Ring, Susan M., Roll, Kathryn, Rudan, Igor, Ruggiero, Daniela, Rujescu, Dan, Salomaa, Veikko, Schlessinger, David, Schmidt, Helena, Schmidt, Reinhold, Schupf, Nicole, Smit, Johannes, Sorice, Rossella, Spector, Tim D., Starr, John M., Stöckl, Doris, Strauch, Konstantin, Stumvoll, Michael, Swertz, Morris A., Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Tönjes, Anke, Tung, Joyce Y., Uitterlinden, André G., Vaccargiu, Simona, Viikari, Jorma, Vitart, Veronique, Völzke, Henry, Vollenweider, Peter, Vuckovic, Dragana, Waage, Johannes, Wagner, Gert G., Wang, Jie Jin, Wareham, Nicholas J., Weir, David R., Willemsen, Gonneke, Willeit, Johann, Wright, Alan F., Zondervan, Krina T., Stefansson, Kari, Krueger, Robert F., Lee, James J., Benjamin, Daniel J., Cesarini, David, Koellinger, Philipp D., den Hoed, Marcel, Snieder, Harold, Mills, Melinda C.
Publicado no Nat Genet (2016)

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

Por Takeuchi, Fumihiko, Akiyama, Masato, Matoba, Nana, Katsuya, Tomohiro, Nakatochi, Masahiro, Tabara, Yasuharu, Narita, Akira, Saw, Woei-Yuh, Moon, Sanghoon, Spracklen, Cassandra N., Chai, Jin-Fang, Kim, Young-Jin, Zhang, Liang, Wang, Chaolong, Li, Huaixing, Li, Honglan, Wu, Jer-Yuarn, Dorajoo, Rajkumar, Nierenberg, Jovia L., Wang, Ya Xing, He, Jing, Bennett, Derrick A., Takahashi, Atsushi, Momozawa, Yukihide, Hirata, Makoto, Matsuda, Koichi, Rakugi, Hiromi, Nakashima, Eitaro, Isono, Masato, Shirota, Matsuyuki, Hozawa, Atsushi, Ichihara, Sahoko, Matsubara, Tatsuaki, Yamamoto, Ken, Kohara, Katsuhiko, Igase, Michiya, Han, Sohee, Gordon-Larsen, Penny, Huang, Wei, Lee, Nanette R., Adair, Linda S., Hwang, Mi Yeong, Lee, Juyoung, Chee, Miao Li, Sabanayagam, Charumathi, Zhao, Wanting, Liu, Jianjun, Reilly, Dermot F., Sun, Liang, Huo, Shaofeng, Edwards, Todd L., Long, Jirong, Chang, Li-Ching, Chen, Chien-Hsiun, Yuan, Jian-Min, Koh, Woon-Puay, Friedlander, Yechiel, Kelly, Tanika N., Bin Wei, Wen, Xu, Liang, Cai, Hui, Xiang, Yong-Bing, Lin, Kuang, Clarke, Robert, Walters, Robin G., Millwood, Iona Y., Li, Liming, Chambers, John C., Kooner, Jaspal S., Elliott, Paul, van der Harst, Pim, Chen, Zhengming, Sasaki, Makoto, Shu, Xiao-Ou, Jonas, Jost B., He, Jiang, Heng, Chew-Kiat, Chen, Yuan-Tsong, Zheng, Wei, Lin, Xu, Teo, Yik-Ying, Tai, E-Shyong, Cheng, Ching-Yu, Wong, Tien Yin, Sim, Xueling, Mohlke, Karen L., Yamamoto, Masayuki, Kim, Bong-Jo, Miki, Tetsuro, Nabika, Toru, Yokota, Mitsuhiro, Kamatani, Yoichiro, Kubo, Michiaki, Kato, Norihiro
Publicado no Nat Commun (2018)

Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus

Por Schulz, Herbert, Ruppert, Ann-Kathrin, Herms, Stefan, Wolf, Christiane, Mirza-Schreiber, Nazanin, Stegle, Oliver, Czamara, Darina, Forstner, Andreas J., Sivalingam, Sugirthan, Schoch, Susanne, Moebus, Susanne, Pütz, Benno, Hillmer, Axel, Fricker, Nadine, Vatter, Hartmut, Müller-Myhsok, Bertram, Nöthen, Markus M., Becker, Albert J., Hoffmann, Per, Sander, Thomas, Cichon, Sven
Publicado no Nat Commun (2017)

What Explains Patterns of Diversification and Richness among Animal Phyla?

Por Jezkova, Tereza, Wiens, John J.
Publicado no Am Nat (2017)

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks

Por Pelikan, Richard C., Kelly, Jennifer A., Fu, Yao, Lareau, Caleb A., Tessneer, Kandice L., Wiley, Graham B., Wiley, Mandi M., Glenn, Stuart B., Harley, John B., Guthridge, Joel M., James, Judith A., Aryee, Martin J., Montgomery, Courtney, Gaffney, Patrick M.
Publicado no Nat Commun (2018)

Variations in Hypoxia Impairs Muscle Oxygenation and Performance during Simulated Team-Sport Running

Por Sweeting, Alice J., Billaut, François, Varley, Matthew C., Rodriguez, Ramón F., Hopkins, William G., Aughey, Robert J.
Publicado no Front Physiol (2017)

Indices of asthma among atopic and non-atopic woodworkers

Por Schlunssen, V, Schaumburg, I, Heederik, D, Taudorf, E, Sigsgaard, T
Publicado em 2004